Kinect(R), the line of motion sensing input devices developed by Microsoft for Xbox One and Xbox 360, provides a natural user interface using gestures for commands. Educational exhibits can be developed that use gestures in active and fun ways to manipulate objects, making Kinect a useful technology for exhibit game play. For Mechanism of Action games (that is, how a pharmaceutical compound works), combining 3D animation with 3D programming provided an eye-catching and entertaining way to learn.